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10 SATURDAY, APRIL 27, 2019                                                                                 THE MORNING CALL















































                  WHAT YOUR


                 HDL cholesterol









                  IS TELLING YOU — AND HOW TO CHANGE IT



             f you’re one of the 102 million Americans diag-  risk factor for cardiovascular mortality. So when  “Dyslipidemia is not just based on any single
             nosed with high cholesterol, it’s likely that your  someone has a very low amount of good choles-  number like LDL cholesterol alone, but that’s all
           Iphysician has spoken to you about managing your  terol in the setting of elevated bad cholesterol,  you hear about – ‘My LDL was this high,’ or, ‘My
            LDL (low-density lipoprotein), the “bad choles-  the risk of dying from a cardiovascular disease is  triglyceride was this high.’ Triglyceride reduction has
            terol” that can lead to buildup in your arteries. As  substantially high.”       not shown any independent benefit to cardiovascular
            a result, you may have been less concerned about  Let’s back up to the basics: Blood cholesterol  mortality,” Dr. Gangar explains.
            your HDL (high-density lipoprotein), which acts as  can be used to estimate an individual’s risk for heart
            a cleanser of sorts and removes cholesterol from  disease, which involves looking at the ratio of total  Statins: The cholesterol-lowering drugs
            the arteries, delivering it to the liver for elimination  cholesterol level to the level of HDL. Total cholesterol  Of the 102 million Americans with high choles-
            from the body.                          includes not only LDL and HDL levels, but also ac-  terol, more than 73 million of them meet the guide-
               It seems simple, right? The directive to lower  counts for levels of triglycerides and VLDL (Very Low  lines that suggest their cholesterol could potentially
            your cholesterol means lowering the overall number.  Density Lipoprotein) – calories consumed that are  be lowered by taking a statin. Statins are drugs that
               Not so fast. There are a number of reasons  burned off and are instead converted into fat.  work by primarily lowering bad cholesterol as well as
            why cholesterol treatment isn’t ‘one size fits all.’ The  An easy way to determine your heart health risk is  moderately increasing HDL , thus reducing vascular
            focus, says Jinal Gangar, MD, MPH at Steward Medi-  to use the ASCVD (Atherosclerotic Cardiovascular  events – and are part of the complexities of medicine
            cal Group’s Easton Hospital, should primarily be on  Disease) Risk Calculator, which was developed as  where there is a bottomless pit of research and
            reducing cardiovascular mortality.      a companion tool to the 2013 American College of  refined clinical questions put into them.
               “There is more consistency, more clinical trials,  Cardiology/American Heart Association Guideline on  As with any prescription, taking a statin as
            and more focus on the LDL. Once we lower the  the Assessment of Cardiovascular Risk. The calculator  a primary prevention should be a collaborative,
            LDL, you have a mortality benefit. Anything in  includes age, sex, race, total cholesterol, HDL choles-  personalized decision between doctor and patient,
            medicine that has a mortality benefit is your top  terol, systolic blood pressure, blood pressure lowering
            priority,” says Dr. Gangar. “HDL is an independent  medication use, diabetes status, and smoking status.  HDL CHOLESTEROL PAGE 11
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