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THE MORNING CALL                                                                                    SATURDAY, MAY 25, 2019   5



               Because GERD exists in four different stages,                                 without damage to the rest of the esophagus. “It
            it is important for doctors to diagnose exactly                                  is a microwave kind of energy, and we take the
            what stage the patient is in so that they know                                   scope and burn out the Barrett’s tissue. You don’t
            what the best treatment option will be.                                          just do the treatment on anyone, however. There is
              In Stage 1, the patient has only minor damage                                  selection criteria,” warns Dr. Mittal. To receive RFA,
            in the esophagus, and medication combined                                        a patient would have to have advanced Barrett’s,
            with lifestyle changes usually helps manage their                                as well as risk factors such as being overweight,
            symptoms. In Stage 2, there is an increase in                                    smoking or drinking alcohol excessively.
            the severity of their symptoms and they should                                     Mittal says that about 95 percent of patients
            consider seeking out a gastroenterologist to help                         1      that receive RFA can go back to work or resume
            them manage their symptoms. In Stage 3, there is                                 normal activity within a day or two, and must stick
            a noticeable decrease in the patient’s quality of life,  When the reflux barrier becomes weak or lax, stomach  to a liquid diet for at least one day.
            and their symptoms can no longer be addressed  acid comes back up into the food pipe, causing GERD.  For some GERD sufferers, valve repair may
            with PPIs. In Stage 4, there is noticeable change to                             be the only way to provide them the relief that
            the affected tissue in the esophagus, which is most                              medications do not. For a long time, an invasive
            likely in patients with years of repeated damage or                              procedure called Nissen fundoplication – where
            patients who took too long to see a doctor.                                      doctors make an incision and then wrap the top of
               “We have established that the acid that comes                                 the stomach around the esophagus to recreate a
            back up into the esophagus causes chemical burn.                                 valve – was the only option. Now, a less invasive,
            Over time, that can transform into something called                              non-surgical procedure called transoral incisionless
                                                                                                            ®
            Barrett’s esophagus. Barrett’s means the lining of                               fundoplication, or TIF , is being performed – with
                                                                                      2      an extremely high success rate – by Amit Sohagia,
                                                                                             MD, gastroenterologist with Easton Hospital.
                                                                                               The procedure, which takes about 45
                                                    A camera called an endoscope is inserted into esophagus
                                                    and provides direct visualization for the TIF® procedure.  minutes to one hour under general anesthesia,
                                                                                             reconstructs the anti-reflux barrier between the
                                                                                             stomach and esophagus by going through the
                                                                                             mouth rather than through an abdominal incision.
                                  Amit Sohagia, MD,                                            “TIF was approved by the FDA in 2007 and
                                                                                                  ®
                                  gastroenterologist                                         we started performing the procedure [at Easton
                                  with Easton Hospital.                                      Hospital] in 2016. Since then, we’ve treated around
                                                                                             130 patients with excellent results. There is no
                                  Photo courtesy of                                          complication in a majority of the patients, and we’ve
                                  Easton Hospital
                                                                                      3      seen a 70 percent success in terms of patients who
                                                                                             are still off their medications,” says Dr. Sohagia.
            the esophagus changes over time from acid burn                                   “Even if they have to take medication, their reflux
            and acid damage,” cautions Dr. Mittal. “Barrett’s  The physician retracts tissue and uses it to create  is much better controlled. After surgery, the
                                                    folds that create a natural reflux barrier.
            is of concern because it increases the risk of                                   medication requirement goes down. They have to
            esophageal cancer. If that keeps happening, any                                  take it as needed, not every day.”
            chemical damage can alter the cells and increase                                   Because TIF involves grabbing the end of
                                                                                                        ®
            the propensity of becoming cancer. Barrett’s does                                the esophagus and wrapping the top of the
            not cause cancer overnight, but over time, it will                               stomach about 270 degrees around it, there are
            increase the risk.”                                                              fasteners involved that take about two weeks
               With an endoscopy or biopsies, doctors can                                    to fully heal, during which time patients must be
            make a diagnosis of Barrett’s, and their patients                                on an entirely liquid to soft diet. Patients may
            routinely follow up with them over the course                                    feel mild, manageable pain for a day or two after
            of a few years to see if it has progressed or not.                        4      the procedure, but not beyond that. After two
            At the same time, the patient works with their                                   weeks patients will notice right away that their
            physician to control the heartburn, which is  Non-absorbable sutures are used to secure the fold.  heartburn symptoms are gone.
            the instigating factor. While many patients are                                    “It’s an instant fix, but it’s not a once-and-done
            diagnosed earlier than Stage 4 of GERD, if they                                  where you are cured for the rest of your life,”
            present with severe heartburn, there are several                                 cautions Dr. Sohagia. “We always tell patients to
            treatment options or procedures available that                                   make sure that they don’t gain too much weight. It’s
            can correct the condition and help them live                                     lifestyle control from that point on – eating small
            symptom-free for the rest of their life.                                         meals, not eating late, and following a diet.”
                                                                                               Dr. Sohagia now trains other physicians in the
                                                                                             procedure and has helped to mine three-year data
            Treatment options: How TIF is                                             5      on TIF outcomes for patients who have been
                                      ®
                                                                                                 ®
            revolutionizing heartburn care                                                   under the care of Easton’s Heartburn Center. For
              In addition to endoscopies and continued  The sutures that are placed help to recreate anatomy  patients who are frustrated with the possibility of
            surveillance of the damaged tissue, there are  and help prevent reflux.           continuing to take PPIs – particularly older people
            treatment options that include therapy to eliminate  Photo courtesy of EndoGastric Solutions ®  or cardiac or lung patients who aren’t candidates for
                                                                                                          ®
            the Barrett’s tissue. One of those techniques is                                 open surgery – TIF is a good alternative.
            called Radio Frequency Ablation (RFA) therapy,                                     “The patients are very happy,” reports Dr. Sohagia.
            which uses heat to cauterize the diseased tissue                                 “And, it’s a very rewarding procedure for us.”
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